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Tocris


Tocris Bioscience是一家專賣生命科學研究化學、多肽和抗體的知名品牌,其產品也廣銷各大藥廠、大學、研究機構,累計超過五萬名科學研究者所采用。 Tocris bioscience是位于英國布里斯托爾的高品質試劑提供商,共有2000多種產品,主要集中在神經科學和信號傳導領域,產品類型包括小分子、多肽、抗體、配體和化合物篩選文庫等,主要產品包括GPCR ligands,神經傳遞素,離子通道調控劑,信號通路抑制劑等,這些產品被廣泛選擇性地用于阻斷或激活生物學通路。Tocris是世界上神經科學研究領域無可爭議的領導者。


Tocris Bioscience is the trading name of Tocris Cookson Ltd., which is headquartered in Bristol, UK. There are approximately 50 employees in the company. In May 2011 Tocris Bioscience was wholly acquired by R&D Systems, headquartered in Minneapolis, MN, USA.Tocris Neuramin was founded in 1982 by Professor Jeff Watkins of the Pharmacology Department at the University of Bristol, UK. Watkins' research interests focused on glutamate receptors and their involvement in the synaptic transmission processes of the mammalian central nervous system. Tocris Neuramin was founded to make standard research tools and novel probes in this field easily available to researchers, at least partly in response to the number of requests for samples Watkins was receiving at the time.


Cookson Chemicals was formed in 1985 by Richard Cookson, Professor of Organic Chemistry at the University of Southampton, UK. Cookson Chemicals provided custom synthesis services as well as a range of neurochemicals to the pharmaceutical and allied industries.Tocris Cookson Ltd was incorporated in the UK in July 1994 as the result of a merger between Tocris Neuramin Ltd of Bristol, UK and Cookson Chemicals Ltd of Southampton, UK. In 2002 Tocris Cookson was awarded The Queen's Awards for Enterprise in the International Trade category and later in 2006 received nominations in five categories of the prestigious Life Science Industry Awards.In October 2005 Tocris announced the opening of new laboratories at the IO Centre, Bristol, UK. At this time, to reflect the increasingly biological nature of the products and customer base the trading name was changed to Tocris Bioscience.


In January 2007 Tocris Bioscience announced the successful completion of a $40 million management buy-out (MBO) deal, providing Tocris with the ability and freedom to further develop its existing business areas and to offer additional products and services to its international client base.In May 2011 Tocris Bioscience announced that it was combining with R&D Systems. R&D Systems' products include a wide selection of biotechnology-based tools for cell biology research including proteins, antibodies, assays and kits. To learn more about the company and their products visit the R&D Systems website.In January 2014 Techne Corporation (NASDAQ: TECH) announced that it will operate under a new trade name, Bio-Techne. Over time the new name will be used to unite the company's resources and portfolio to deliver its best-in-class brands and service solutions under a new unified website. The company's major brand names, including Tocris Bioscience, will be maintained.In January 2016 Tocris Bioscience relocated to a brand new facility at the Avonbridge Trading Estate, Bristol, UK. The facility was named the Watkins Building, after Jeff Watkins, who founded Tocris Neuramin in 1982. At this time the Tocris catalog also surpassed 4000 products.


產品列表:


Tocris

1000/10

ZD 7288 (10 MG)

10 MG

Tocris

1000/50

ZD 7288 (50 MG)

50 MG

Tocris

1001/10

Chlorisondamine diiodide (10 MG)

10 MG

Tocris

1001/50

Chlorisondamine diiodide (50 MG)

50 MG

Tocris

1002/10

L-745,870 trihydrochloride (10 MG)

10 MG

Tocris

1002/50

L-745,870 trihydrochloride (50 MG)

50 MG

Tocris

1003/10

L-741,626 (10 MG)

10 MG

Tocris

1003/50

L-741,626 (50 MG)

50 MG

Tocris

1004/10

L-741,742 hydrochloride (10 MG)

10 MG

Tocris

1004/50

L-741,742 hydrochloride (50 MG)

50 MG

Tocris

1006/10

BMY 7378 dihydrochloride (10 MG)

10 MG

Tocris

1006/50

BMY 7378 dihydrochloride (50 MG)

50 MG

Tocris

1007/10

N-Desmethylclozapine (10 MG)

10 MG

Tocris

1007/50

N-Desmethylclozapine (50 MG)

50 MG

Tocris

1009/10

E4CPG (10 MG)

10 MG

Tocris

1009/50

E4CPG (50 MG)

50 MG

Tocris

1014/100

QX 314 bromide (100 MG)

100 MG

Tocris

1015/10

RS 16566 dihydrochloride (10 MG)

10 MG

Tocris

1015/50

RS 16566 dihydrochloride (50 MG)

50 MG